Recently, Hsu and her colleagues found a way to bioengineer a less toxic substitute for synthetic indigo. They tweaked the DNA, or hereditary material, of E. coli bacteria to produce a chemical found in I. tinctura plants. This chemical can dye cloth blue when mixed with an enzyme—a substance that helps speed up chemical reactions.
It’s too soon to tell whether this indigo alternative could someday replace the synthetic version. “The next step is to see if we can make a pair of jeans using our method,” says Hsu. Until then, your blue jeans will still be blue—just not entirely green.